High BMI Associated with Low Survival Rate Among Women with Breast Cancer
By Hugh C. McBride
A British study has documented an association between higher body mass index (BMI) and lower survival rates in women who have been diagnosed with breast cancer.
The study, which was led by Dr. Gillian C. Barnett of Addenbrooke's Hospital in Cambridge, United Kingdom, found that women with a BMI of 28.5 or higher were 52 percent more likely to die than were women whose BMI was 22.7 or lower.
"We have found strong evidence that high BMI and a recent pregnancy are associated with a poorer prognosis after a diagnosis of breast cancer," Barnett told Dr. Will Boggs of Reuters Health. "Our study suggests that advice on weight loss should be given to all obese patients with breast cancer."
Barnett and her colleagues reached their conclusions after analyzing data that had been collected during the Studies of Epidemiology and Risk Factors in Cancer Heredity. Though the group's findings are alarming, Barnett cautioned that additional research is necessary in order to confirm and quantify the risk faced by obese women who have breast cancer.
"Further definitive clinical weight loss intervention trials in breast cancer populations are required to further clarify the relationship between breast cancer mortality and BMI," she said.
The study was published in the July 10, 2008, edition of the Journal of Clinical Oncology.
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